Kinase Drug Discovery: Modern Approaches
de: Richard A. Ward
Publicat de: Royal Society of Chemistry
Anunta-ma cand revine pe stoc!Kinase targets and drugs remain an area of significant interest across academia and in the pharmaceutical industry. There are now many marketed drugs which target kinases and a growing number of compounds are currently in various stages of clinical development. This book covers the key areas for kinase inhibition that will be important over the coming years. This will be an important reference for scientists involved in drug discovery in academia or industry, particularly in oncology research.
About the AuthorDr Frederick W Goldberg is a Medicinal Chemist at AstraZeneca, UK. He received his MSci at Cambridge University, PhD at Imperial College London and a Postdoc (Fulbright scholarship) at the University of Texas at Austin. He has extensive experience of leading both chemistry and project teams within oncology, including targets that have delivered clinical candidates. He has over 30 published papers and patents, including a number of research papers and perspective articles on kinases. Dr Richard A Ward is a Computational Medicinal Chemist at AstraZeneca, UK. He received his BSc (Hons) in Chemistry with Bio-organic Chemistry at The University of Birmingham and gained a PhD in Computational Chemistry also at The University of Birmingham, under the supervision of Dr John Wilkie. He has extensive experience in target selection, lead generation and lead optimisation against kinase and non-kinase targets with a specialisation in covalent drug discovery. Along with publishing a number of papers on kinases, Richard is a co-inventor of the EGFR mutant kinase inhibitor osimertinib.
General | |
Anul | 2018 |
Autor | Richard A. Ward |
Cod de bare | 9781788010832 |
Editura | Royal Society of Chemistry |
Dimensiuni | 233.7 x 162.6 |
ISBN | 1788010833 |
Limba | Engleza |
Pagini | 413 |
Format | Cartonata |